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By Susan D. Brienza. Ph.D., Esq., Ryley Carlock & Applewhite Introduction While many Americans have used the COVID-19 pandemic as an opportunity to come together, some unscrupulous businesses have sought to turn pandemonium into profit. As of today, no prevention, remedy, or vaccine is known to exist for COVID-19. Therefore, any coronavirus-related “treatment” or other medical products and claims are not substantiated by competent and reliable scientific evidence. Moreover, any future COVID-19 drugs must be first approved by the Food and Drug Administration (FDA). In an attempt to prevent deception and fraud during these confusing and stressful times, the FDA, the Federal Trade Commission (FTC), and the Environmental Protection Agency (EPA) have cracked down on unfair business and marketing practices at an unprecedented rate. This article analyzes numerous examples of recent warning letters regarding unapproved and/or unsupported products and claims related to COVID-19, and emphasizes the need for all companies to adhere to FDA/FTC/EPA regulations. Agency Teamwork to Tackle Fraud Since the beginning of the COVID-19 pandemic in the U.S. in March, the FTC and FDA have partnered in sending more than 40 warning letters to companies regarding fraudulent claims that their products can prevent, treat, or cure COVID-19. The agencies have cited extensive language on the companies’ websites and social media channels as evidence of these deceptive claims. Most dietary supplement companies are “good players,” with only a small minority of bad and opportunistic apples. With confidence in the majority’s desire for compliance, the four leading trade associations1 (Coalition) for the supplement industry jointly released a unified advisory statement in February as a proactive measure.2 This statement cautioned markete